How can I troubleshoot high or increasing system backpressure?
- Integrion models:
Possible causes and solutions:
1. Restriction in the system plumbing
- If the pump pressure limit was tripped, isolate the restriction by working forward through the system, adding parts one at a time until an abnormal pressure increase (and hence, the restriction) is found.
- If the pump pressure limit was not tripped, you can isolate the restriction by working backward through the system.
- Correct the restriction.
2. Sample precipitating in or adsorbing to the column
- Filter the sample.
- Dilute the sample.
- Run the sample through an OnGuard cartridge or an InGuard cartridge.
3. Mismatched eluent or organic solvent
- Refer to the column manual for the correct eluent or solvent for your application.
4. Column temperature too low
- Make sure the column is installed correctly on the column clips and the column compartment door is closed completely.
- Check the temperature setpoint of the column compartment.
- If the compartment is set at the correct temperature and the reading is stable, use an external temperature probe to measure the temperature.
- If the reading does not match the temperature reported by the system, the column compartment heater many need to be replaced. Contact Technical Support for Dionex products for assistance.