Skip to main content
Thermo Fisher Scientific

AN 51115 - The On-Line Monitoring of Powder Blending in a Bin Blender


A revolutionary miniature near-infrared analyzer, the Antaris™Target, is used in a case study to predict blend uniformity on a bin blender in a pharmaceutical manufacturing plant. Without the need for precalibrated chemometric methods, as is the norm for most NIR analytics, the Antaris Target blend analyzer uses a moving window standard deviation for prediction. In this application,we show that the Antaris Target can be successfully incorporated into moving pharmaceutical manufacturing processes and give highly accurate, critical in-process data about blend homogeneity.


  • Antaris™Target
  • Near IR