Negative peaks
Issue
How to troubleshoot if the unit is experiencing negative peaks?
Environment
- Vanquish Flex Binary UHPLC System
- Vanquish Flex Quaternary UHPLC System
Resolution
| POSSIBLE CAUSE | REMEDIAL ACTION |
| Improper reference wavelength | The sample must not absorb in the range of the reference wavelength. Consider using a method without reference wavelength. |
| Wrong polarization of analog output | If you are using analog output, check the analog output polarization. |
For additional troubleshooting help try downloading the Thermo Scientific HPLC Troubleshooting Guide App. The app is an extensive tool to effectively diagnose various potential issues with HPLC analysis.
Thermo Scientific HPLC Troubleshooting Guide App (Apple App Store)
Thermo Scientific HPLC Troubleshooting Guide App (Google Play)