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Thermo Fisher Scientific

How to Replace the Piston Seals and Support Ring

Issue

  • Excessive seal leakage leads to retention time shifts and increased baseline noise; or
  • Pump head removed

Environment

Vanquish HPLC and UHPLC systems

Resolution

Replace the piston seals of your pump on a regular basis or whenever excessive seal leakage leads to retention time shifts and increased baseline noise. Replace the seal wash seals whenever you remove the pump head. You need not replace the support ring when you replace a piston seal. Replace the support ring only when applicable.

Required parts:
  • New piston seals
  • New seal wash seals
  • Seal handling tool
  • Syringe filled with isopropanol
Preparation steps:
  1. Remove the pump head (see “How to Replace the Pump Head”)
  2. Remove the pistons
  3. Remove the seal wash plate from the pump head

Analysis

The Vanquish HPLC and UHPLC systems offer uncompromised performance, robustness, and ease of use. A key element of its user-friendly functionality is the accessibility of the system for simple maintenance and replacement procedures. These videos provide step-by-step instructions on how to perform these procedures and keep your Vanquish HPLC and UHPLC systems operating smoothly. To access these procedures from your instrument, without the need for an external internet connection, consider adding the Vanquish User Interface to your system.

 

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