Correcting Restrictions

Issue

How can I correct restrictions?

Environment

• Integrion models:
  • 22153-60301
  • 22153-60302
  • 22153-60303
  • 22153-60304
  • 22153-60305
  • 22153-60306

Resolution

Possible Causes and Solutions:

1. Tubing or fitting

• Back flush or replace the tubing or fitting. Be careful not to overtighten fittings.

2. Column

• Replace the column inlet bed support or clean the column.
• For instructions, refer to the column manual provided on the Thermo Scientific Reference Library DVD (P/N 60-053891).
• If sample precipitation adsorbing onto the column is suspected, filter or dilute the sample, or run the sample through an OnGuard cartridge or InGuard cartridge.

3. Injection valve 

• If the injection valve is the suspected source of the high backpressure, observe a run to see whether the high-pressure limit is triggered when injection occurs; if it is, the injection valve rotor seal or stator may need to be replaced.

4. Dionex EGC III 

• Replace the outlet frit as instructed in the Dionex EGC manual.
• The manual is provided on the Thermo Scientific Reference Library DVD (P/N 60-053891).